Anaplastic large cell lymphoma, ALK-negative

Definition

A T-cell peripheral lymphoma morphologically indistinguishable from anaplastic large cell lymphoma, ALK-positive. It is characterised by the absence of the translocation involving the ALK gene and lacks expression of ALK fusion protein.

Exclusions

• Primary cutaneous CD30-positive T-cell lymphoproliferative disorders (2B03)

Also indexed as

Nearby in Mature T-cell lymphoma, specified types, nodal or systemic

• 2A90.0T-cell prolymphocytic leukaemia
• 2A90.1T-cell large granular lymphocytic leukaemia
• 2A90.2Chronic lymphoproliferative disorders of NK-cells
• 2A90.3Aggressive NK cell leukaemia
• 2A90.4Systemic Epstein-Barr Virus-positive T-cell lymphoma of childhood
• 2A90.5Adult T-cell lymphoma or leukaemia, human T-cell lymphotropic virus type 1-associated
• 2A90.6Extranodal NK/T-cell lymphoma, nasal type
• 2A90.7Enteropathy associated T-cell lymphoma