Sickle cell disorders or other haemoglobinopathies

Definition

Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may present with fatigue, shortness of breath, dizziness, headaches, pallor of skin or mucous membranes, and jaundice. This disorder is confirmed by identification of HbS mutation by genetic testing.

14 subordinate codes

• 3A51.0Sickle cell trait
• 3A51.1Sickle cell disease without crisis
• 3A51.2Sickle cell disease with crisis
• 3A51.3Compound heterozygous sickling disorders without crisis
• 3A51.4Compound heterozygous sickling disorders with crisis
• 3A51.5Haemoglobin C disease
• 3A51.6Haemoglobin D disease
• 3A51.7High affinity haemoglobin
• 3A51.8Low affinity haemoglobin
• 3A51.9Haemoglobin O disease
• 3A51.AHaemoglobin E disease
• 3A51.BHaemoglobin C/beta thalassaemia compound heterozygosity
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified

Nearby in Anaemias or other erythrocyte disorders

• 3A00-3A0ZNutritional or metabolic anaemias
• 3A10-3A4ZHaemolytic anaemias
• 3A50Thalassaemias
• 3A60-3A6ZPure red cell aplasia
• 3A70Aplastic anaemia
• 3A71Anaemia due to chronic disease
• 3A72Sideroblastic anaemia
• 3A73Congenital dyserythropoietic anaemia