Haemoglobin O disease

Definition

A disease caused by the bi-parental inheritance of the gene that encodes for haemoglobin O. This disease is characterised by abnormal structure of one of the globin chains of the haemoglobin molecule. This disease may present with mild haemolytic anaemia, increased risk for gallstones, enlarged spleen, episodes of joint pain, and increased risk of infection. This disease is confirmed by identification of the haemoglobin O gene by genetic testing.

Also indexed as

Nearby in Sickle cell disorders or other haemoglobinopathies

• 3A51.0Sickle cell trait
• 3A51.1Sickle cell disease without crisis
• 3A51.2Sickle cell disease with crisis
• 3A51.3Compound heterozygous sickling disorders without crisis
• 3A51.4Compound heterozygous sickling disorders with crisis
• 3A51.5Haemoglobin C disease
• 3A51.6Haemoglobin D disease
• 3A51.7High affinity haemoglobin