Fibronectin glomerulopathy

Definition

Fibronectin glomerulopathy is a rare hereditary kidney disease in which fibronectin (FN1) deposits are seen in the mesangium and subendothelial space. The clinical picture is characterised by proteinuria, type IV renal tubular acidosis, microscopic haematuria and hypertension that may lead to end-stage renal failure in the second to sixth decade of life. This disease may be associated with mutations in the FN1 gene.

Also indexed as

Nearby in Clinical findings in specimens from the urinary system

• MF80Diffuse mesangial sclerosis
• MF82Lipoprotein glomerulopathy
• MF83Diabetic glomerular changes
• MF84Pauci-immune proliferative glomerulonephritis
• MF85Anti-glomerular basement membrane antibody mediated disease
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified