ICD·index Chapters ENESDE
5B5G category

Deficiencia de biotina

Definition

In infants on biotin-free TPN, symptoms of biotin deficiency begin to appear within 3 to 6 months after initiation of the TPN regimen, which is earlier than that seen in adults, probably because of the increased biotin requirement related to growth. The associated rash appears first around the mouth, eyes, and nose. The rash and the unusual distribution of facial fat observed in these infants together are called biotin deficiency facies. As the rash progresses, the ears and perineal orifices are affected. In biotin-deficient infants, hypotonia, lethargy, and developmental delay, along with a peculiar withdrawn behavior, are all characteristic of a neurological disorder resulting from a lack of biotin. [No translation available]

Also indexed as

Deficiencia de biotinacarencia de biotinacarencia del complejo de avidina y biotinadeficiencia de vitamina biotandéficit de biotinaenfermedad por deficiencia de biotinainsuficiencia de biotina

Nearby in Desnutrición