ICD·index Chapters ENESDE
8A44.1 category

Adrenoleukodystrophy

Definition

X-linked genetic disorder associated with accumulation of very-long-chain fatty acids in the brain and adrenal cortex due to a mutation in the ABCD1 gene causing defects in peroxisomal oxidation. Neurological symptoms can present in childhood or adulthood with almost all patients having concurrent adrenal insufficiency.

Also indexed as

ADLD - [adult-onset autosomal dominant leukodystrophy]ALD - [adrenoleukodystrophy]Addison-SchilderAdrenoleukodystrophyAdult-onset autosomal dominant leukodystrophyAutosomal dominant Pelizaeus-Merzbacher diseaseMultiple sclerosis-like disorder

Nearby in Leukodystrophies