Chronic eosinophilic leukaemia, not elsewhere classified

Definition

A chronic myeloproliferative neoplasm characterised by persistent eosinophilia in the blood, bone marrow and peripheral tissues. Organ damage occurs as a result of leukaemic infiltration or the release of cytokines, enzymes or other proteins by the eosinophils. Chronic eosinophilic leukaemia, not otherwise specified excludes patients with a Ph chromosome, BCR-ABL1 fusion gene or rearrangement of PDGFRA, PDGFRB or FGFR1.

Also indexed as

Nearby in Non mast cell myeloproliferative neoplasms

• 2A20.0Chronic myelogenous leukaemia, BCR-ABL1-positive
• 2A20.1Chronic neutrophilic leukaemia
• 2A20.2Primary myelofibrosis
• 2A20.4Polycythaemia vera
• 2A20.5Non mast cell myeloproliferative neoplasm, unclassifiable
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified