8A00.01
category
Familial Parkinson disease
Definition
Familial subtype of Parkinson Disease, a disorder caused by progressive dopaminergic neuron degeneration of the substantia nigra that is characterized by resting tremor, bradykinesia, and rigidity. Familial cases can be caused by mutations in LRRK2, PARK7, PINK1, PRKN, or SNCA genes.
Also indexed as
Autosomal dominant familial Parkinson diseaseAutosomal recessive familial Parkinson diseaseFamilial Parkinson diseaseOther genetic ParkinsonismPARK 2PARK 6PARK 7PARK1PARK5PARK8PINK 1Parkinson disease ATP13A2 mutationsParkinson disease DJ-1 gene mutations 1p36Parkinson disease LRRK2 gene mutation 12p11.23-q13.11Parkinson disease PINK gene mutationsParkinson disease UCHL-1 gene mutations 4p14Parkinson disease parkin mutationsParkinson disease synduclein duplications or triplicationsParkinson disease synuclein gene mutation 4q21.23