2B5A
category
Synovial sarcoma, primary site
Definition
A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes.
4 subordinate codes
Nearby in Malignant mesenchymal neoplasms
2B50Chondrosarcoma, primary site2B51Osteosarcoma, primary site2B52Ewing sarcoma, primary site2B53Fibroblastic or myofibroblastic tumour, primary site2B54Undifferentiated pleomorphic sarcoma, primary site2B55Rhabdomyosarcoma, primary site2B56Angiosarcoma, primary site2B57Kaposi sarcoma, primary site