20Developmental anomalies Structural developmental anomalies primarily affecting one body system Structural developmental anomalies of the eye, eyelid or lacrimal apparatus LA12Structural developmental anomalies of lens or zonula
LA12.3
category
Spherophakia
Definition A disease of the eye, caused by homozygous mutations in the LTBP2 gene (isolated spherophakia), or by other genetic mutations. This disease is characterised by small, spherical lenses. This disease can also present with lenticular myopia, glaucoma, or sublation of the lens into the vitreous cavity.
Also indexed as
Spherophakia Spherophakia, bilateral Spherophakia, unilateral congenital spherophakia microspherophakia NOS microspherophakia NOS, bilateral microspherophakia NOS, unilateral
Nearby in Structural developmental anomalies of lens or zonula
International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO) 2019/2021, https://icd.who.int/browse11. Licensed under Creative Commons Attribution-NoDerivatives 3.0 IGO (CC BY-ND 3.0 IGO).
Release 2026-01.
View this entity in the official WHO ICD-11 browser .
This page reproduces WHO classification content for reference. It is not
medical advice and must not be used to diagnose or treat. For coding
decisions, consult the official release and your national coding guidelines.
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