Systemic-onset juvenile idiopathic arthritis represents 10-11% of cases of juvenile idiopathic arthritis (JIA) and is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio. Fever peaks are associated with transient cutaneous eruptions and diffuse erythematosis or urticarial-like lesions. The presence of arthritis is essential for diagnosis but may appear later in the disease course. The number of sites affected is variable (mono-, oligo- or polyarthritis) affecting both the small and large joints in a nearly symmetrical manner. This characteristic diagnostic triad may also be associated with an adenopathy and hepatosplenomegaly. Visceral complications (pericarditis, pleural effusion or serous peritonitis with abdominal pain) may be present.
Also indexed as
Juvenile systemic arthritisJuvenile systemic arthritis, acromioclavicular jointJuvenile systemic arthritis, ankle jointJuvenile systemic arthritis, ankle or footJuvenile systemic arthritis, carpusJuvenile systemic arthritis, elbow jointJuvenile systemic arthritis, fingersJuvenile systemic arthritis, forearmJuvenile systemic arthritis, glenohumeral jointJuvenile systemic arthritis, handJuvenile systemic arthritis, headJuvenile systemic arthritis, hip jointJuvenile systemic arthritis, knee jointJuvenile systemic arthritis, lower legJuvenile systemic arthritis, metacarpusJuvenile systemic arthritis, metatarsusJuvenile systemic arthritis, multiple sitesJuvenile systemic arthritis, neckJuvenile systemic arthritis, other joints in footJuvenile systemic arthritis, pelvic region or thighJuvenile systemic arthritis, shoulder regionJuvenile systemic arthritis, sternoclavicular jointJuvenile systemic arthritis, tarsusJuvenile systemic arthritis, toesJuvenile systemic arthritis, upper armJuvenile systemic arthritis, vertebral columnJuvenile systemic arthritis, wrist jointJuvenile systemic onset arthritis complicated by macrophage activation syndromeStill diseasejuvenile arthritis with systemic onset, ankle or footjuvenile arthritis with systemic onset, forearmjuvenile arthritis with systemic onset, handjuvenile arthritis with systemic onset, lower legjuvenile arthritis with systemic onset, multiple sitesjuvenile arthritis with systemic onset, pelvic region or thighjuvenile arthritis with systemic onset, shoulder regionjuvenile arthritis with systemic onset, upper armjuvenile arthritis with systemic onset, wrist joint