Neuromyelitis optica aquaporin-4 antibody negative

Definition

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system characterised mainly by attacks of uni- or bilateral optic neuritis (ON) and acute longitudinally extensive (> 3 vertebral segments) myelitis. This form is seronegative for aquaporin-4 antibodies. Some patients may be myelin oligodendrocyte glycoprotein (MOG) antibody positive.

Also indexed as

Nearby in Neuromyelitis optica

• 8A43.0Neuromyelitis optica aquaporin-4 antibody positive
• 8A43.2Single transverse myelitis aquaporin-4 antibody positive
• 8A43.3Recurrent transverse myelitis aquaporin-4 antibody positive
• 8A43.4Single optic neuritis aquaporin-4 antibody positive
• 8A43.5Recurrent optic neuritis aquaporin-4 antibody positive
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified