Idiopathic central alveolar hypoventilation

Definition

Idiopathic central alveolar hypoventilation is defined as the presence of decreased alveolar ventilation resulting in sleep related hypercapnia and hypoxemia in individuals with presumed normal mechanical properties of the lung and respiratory pump. Chronic hypoventilation during sleep exists without any readily identifiable impairments of respiration, such as pulmonary airway or parenchymal conditions, neurologic, neuromuscular or chest wall abnormalities, severe obesity, other sleep related breathing disorder, or use of respiratory depressant medications or substances. Diurnal as well as nocturnal hypoventilation is believed to be due primarily to blunted chemoresponsiveness to carbon dioxide (CO2) and oxygen (O2). Patients may complain of morning headaches, fatigue, neurocognitive decline and sleep disturbance, or may be entirely asymptomatic. Note: A definitive diagnosis requires objective evidence based on polysomnography with carbon dioxide (CO2) monitoring (by arterial, end-tidal or transcutaneous measures).

Also indexed as

Nearby in Sleep-related hypoventilation or hypoxemia disorders

• 7A42.0Obesity hypoventilation syndrome
• 7A42.1Congenital central alveolar sleep-related hypoventilation
• 7A42.2Non-congenital central hypoventilation with hypothalamic abnormalities
• 7A42.4Sleep-related hypoventilation due to a medication or substance
• 7A42.5Sleep-related hypoventilation due to medical condition
• 7A42.6Sleep-related hypoxemia due to a medical condition
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified