Opioid intoxication
Definition
Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of opioids and their intensity is closely related to the amount of opioids consumed. They are time-limited and abate as opioids are cleared from the body. Presenting features may include somnolence, stupor, mood changes (e.g. euphoria followed by apathy and dysphoria), psychomotor retardation, impaired judgment, respiratory depression, slurred speech, and impairment of memory and attention. In severe intoxication coma may ensue. A characteristic physical sign is pupillary constriction but this sign may be absent when intoxication is due to synthetic opioids. Severe opioid intoxication can lead to death due to respiratory depression.
Exclusions
- Possession trance disorder
(6B63) - fentanyl poisoning
(NE60) - opioid poisoning
(NE60) - oxycodone poisoning
(NE60)
Also indexed as
Nearby in Disorders due to use of opioids
6C43.0Episode of harmful use of opioids6C43.1Harmful pattern of use of opioids6C43.2Opioid dependence6C43.4Opioid withdrawal6C43.5Opioid-induced delirium6C43.6Opioid-induced psychotic disorder6C43.7Certain specified opioid-induced mental or behavioural disorders4B4YOther specified diseases of the immune system