02Neoplasms In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues 2E67Carcinoma in situ of other or unspecified genital organs 2E67.1Carcinoma in situ of vulva
2E67.12
category
Vulvar intraepithelial neoplasia, HPV-independent
Definition Vulvar intraepithelial neoplasia (VIN), HPV-independent, is a non-invasive precursor of HPV-independent squamous cell carcinoma of the vulva, characterized by atypia of the basal and parabasal keratinocytes in an otherwise well-differentiated epithelium.
Also indexed as
DVIN [Differentiated vulvar intraepithelial neoplasia] Differentiated vulvar intraepithelial neoplasia Vulvar intraepithelial neoplasia grade III, simplex (deprecated) Vulvar intraepithelial neoplasia grade III, simplex, differentiated type, non-HPV associated (deprecated) Vulvar intraepithelial neoplasia, HPV-independent Vulvar intraepithelial neoplasia, differentiated (dVIN)
Nearby in Carcinoma in situ of vulva
International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO) 2019/2021, https://icd.who.int/browse11. Licensed under Creative Commons Attribution-NoDerivatives 3.0 IGO (CC BY-ND 3.0 IGO).
Release 2026-01.
View this entity in the official WHO ICD-11 browser .
This page reproduces WHO classification content for reference. It is not
medical advice and must not be used to diagnose or treat. For coding
decisions, consult the official release and your national coding guidelines.
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