Malignant neoplasms of kidney, except renal pelvis
Definition
Cancer of the kidney amounts to 2% of the total human cancer burden, with approximately 190,000 new cases diagnosed each year. They occur in all world regions, with a preference for developed countries. Etiological factors include environmental carcinogens (tobacco smoking) and lifestyle factors, in particular obesity. Although renal tumours can be completely removed surgically, haematogeneous metastasis is frequent and may occur already at an early stage of the disease. The pattern of somatic mutations in kidney tumours has been extensively investigated and has become, in addition to histopathology, a major criterion for classification. Kidney tumours also occur in the setting of several inherited cancer syndromes, including von Hippel-Lindau disease.
Exclusions
3 subordinate codes
Nearby in Malignant neoplasms of urinary tract
2C91Malignant neoplasms of renal pelvis2C92Malignant neoplasms of ureter2C93Malignant neoplasms of urethra or paraurethral gland2C94Malignant neoplasms of bladder2C95Malignant neoplasm involving overlapping sites of urinary organs4B4YOther specified diseases of the immune system4B4ZDiseases of the immune system, unspecified