Inflammatory carcinoma of breast

Definition

An advanced, invasive breast adenocarcinoma characterised by the presence of distinct changes in the overlying skin. These changes include diffuse erythema, edema, peau d'orange (skin of an orange) appearance, tenderness, induration, warmth, enlargement, and in some cases a palpable mass. The skin changes are the consequence of lymphatic obstruction from the underlying invasive breast adenocarcinoma. Microscopically, the dermal lymphatics show prominent infiltration by malignant cells. The invasive breast adenocarcinoma is usually of ductal, NOS type. There is not significant inflammatory cell infiltrate present, despite the name of this carcinoma.

Also indexed as

Nearby in Malignant neoplasms of breast

• 2C60Carcinoma of breast, specialised type
• 2C61Invasive carcinoma of breast
• 2C63Malignant phyllodes tumour of breast
• 2C64Solid papillary carcinoma of breast with evidence of invasion
• 2C65Hereditary breast and ovarian cancer syndrome
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified