Early-onset parkinsonism - intellectual deficit

Definition

Early-onset parkinsonism with intellectual deficit is a basal ganglia disorder characterised by parkinsonian-type symptoms (postural changes, tremor, rigidity), megalencephaly and variable intellectual deficit. Other signs are frontal bossing, persistent frontal lobe reflexes, strabismus and seizures.

Also indexed as

Nearby in Conditions with disorders of intellectual development as a relevant clinical feature

• LD90.0Angelman syndrome
• LD90.2Pelizaeus-Merzbacher-like disease
• LD90.3Prader-Willi syndrome
• LD90.4Rett syndrome
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified