Necrotising enterocolitis of newborn

Definition

This is a fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal haemorrhage, and necrosis usually of the right colon, caecum, terminal ileum, and appendix (ENTEROCOLITIS), possibly due to perinatal intestinal ischemia and bacterial invasion. The entire colon, small intestine, stomach, and oesophagus may also be affected. Most infants are premature or suffer from respiratory distress syndrome, sepsis, or hypoxia. Symptoms (apparent during the first few weeks of life) include abdominal distension, bilious vomiting, and melaena; there may be apnoea, lethargy, temperature instability, tachycardia, tachypnoea, and a fall in blood pressure. The disorder may progress to perforation and peritonitis.

6 subordinate codes

• KB88.0Necrotising enterocolitis of newborn, Stage 1A & B
• KB88.1Necrotising enterocolitis of newborn, Stage 2A & B
• KB88.2Necrotising enterocolitis of newborn, Stage 3A
• KB88.3Necrotising enterocolitis of newborn, Stage 3B
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified

Nearby in Digestive system disorders of fetus or newborn

• KB80Gastro-oesophageal reflux disease in newborn
• KB81Oesophagitis in newborn
• KB82Prenatal gastric perforation
• KB83Postnatal gastric perforation
• KB84Postnatal isolated ileal perforation
• KB85Prenatal intrauterine intestinal perforation
• KB86Postnatal intestinal perforation
• KB87Intestinal obstruction of newborn