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DNA instability syndromes affecting the skin
Definition
A range of disorders characterised by DNA damage and defective DNA repair. Clinical features of relevance to the skin and external appearance include dysmorphic features, photosensitivity and an increased tendency to skin cancer.
Nearby in Genetic or developmental disorders affecting the skin
EC10-EC1YGenetic syndromes affecting the skinEC20Genetic disorders of keratinisationEC21Genetic defects of hair or hair growthEC22Genetic defects of nails or nail growthEC23Genetic disorders of skin pigmentationEC30-EC3ZGenetically-determined epidermolysis bullosaEC40-EC4YGenetic disorders affecting dermal collagen, elastin or other matrix proteinsEC50-EC5YSpecified developmental anomalies affecting the skin