Alpha, alpha trehalase deficiency

Definition

Alpha, alpha trehalase deficiency is characterised by diarrhoea and vomiting after ingestion of trehalose, a disaccharide found mainly in mushrooms. The disease is very rare in most populations but the incidence has been estimated at least 1 in 13 in Greenland. Isolated trehalose intolerance is due to a deficiency of trehalase (TREH; 11q23.3), a brush-border membrane glycoprotein.

Also indexed as

Nearby in Disorders of carbohydrate absorption or transport

• 5C61.0Glucose-galactose malabsorption
• 5C61.1Maltase-glucoamylase deficiency
• 5C61.2Congenital sucrase-isomaltase deficiency
• 5C61.4Acquired monosaccharide malabsorption
• 5C61.5Disorders of facilitated glucose transport
• 5C61.6Lactose intolerance
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified