Anaphylaxis secondary to mast cell disorder

Definition

Symptoms of anaphylaxis secondary to mast cell disorders result from excessive mast cell mediator release, especially histamine, and may include pruritus and flushing, abdominal pain, diarrhea, dyspnoea, tachycardia, or profound hypotension. It happens in both children and adults, but in adults it can occur even without urticaria pigmentosa lesions. Levels of basal tryptase are constantly high. Fatal anaphylaxis has been described following hymenoptera stings and in the preoperative period.

Also indexed as

Nearby in Anaphylaxis

• 4A84.0Anaphylaxis due to allergic reaction to food
• 4A84.1Drug-induced anaphylaxis
• 4A84.2Anaphylaxis due to insect venom
• 4A84.3Anaphylaxis provoked by physical factors
• 4A84.4Anaphylaxis due to inhaled allergens
• 4A84.5Anaphylaxis due to contact with allergens
• 4B4YOther specified diseases of the immune system
• 4B4ZDiseases of the immune system, unspecified